BioMed Central Breast Cancer Research
Inflammatory breast cancer (IBC) is the most lethal form of breast cancers with a 5-year survival rate of only 40 %. Despite its lethality, IBC remains poorly understood which has greatly limited its therapeutic management. We thus decided to utilize an integrative functional genomic strategy to identify the Achilles’ heel of IBC cells.
Putcha, Preeti; Yu, Jiyang; Rodriguez-Barrueco, Ruth; Saucedo-Cuevas, Laura; Villagrasa, Patricia; Murga-Penas, Eva; Quayle, Steven N.; Yang, Min; Castro, Veronica; Llobet-Navas, David; Birbaum, Daniel; Finetti, Pascal; Woodward, Wendy A.; Bertucci, Francois; Alpaugh, Mary; Califano, Andrea; and Silva, Jose, "HDAC6 activity is a non-oncogene addiction hub for inflammatory breast cancers" (2015). Faculty Scholarship for the College of Science & Mathematics. 16.