Author(s)

Sivaram Karra

Date Approved

10-19-2015

Embargo Period

12-21-2015

Document Type

Thesis

Degree Name

M.S. Electrical and Computer Engineering

Department

Electrical and Computer Engineering

College

Henry M. Rowan College of Engineering

First Advisor

Head, Linda

Subject(s)

Near infrared spectroscopy;Brain--Diagnostic imaging

Disciplines

Electrical and Computer Engineering

Abstract

An established, non-invasive and flexible technique, "functional Near Infra-Red Spectroscopy" (fNIRS), has opened new opportunities for the study of brain functionality. This powerful method uses the optical properties of a tissue at multiple near infra-red wavelengths to dynamically determine the levels of both oxygenated hemoglobin (HbO2) and deoxygenated hemoglobin (Hbr). Traditional techniques such as functional Magnetic Resonance Imaging (fMRI), Positron Emission Tomography (PET), Electroencephalography (EEG) and Event Related brain Potentials (ERP) have increased our understanding of brain functionality, however, the basic limitations of these technologies such as high cost of equipment, difficulty of operation and levels of radiation make access limited for researchers exploring brain function in real-time environments. The purpose of this work is to demonstrate the enhancement of the existing single photodiode wireless fNIRS sensor to two photodiode wireless fNIRS sensor for brain imaging using Bluetooth technology. This enhanced design allows arbitrary positioning of sensors that are able to detect HbO2 and Hbr response at multiple positions in the cerebral cortex.

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