Date of Presentation

5-2-2024 12:00 AM

College

Rowan-Virtua School of Osteopathic Medicine

Poster Abstract

Alzheimer's disease (AD) and MCI are a major concern in modern neuropsychiatric care, chiefly for their difficult management. This strategic literature review categorizes MCI via the Jak-Bondi criteria and relates it to tES treatment paradigms. Commonly used outcome measures and regional brain mapping data synergizes associations between MCI pathology and potential tES treatment targets. Effect sizes were calculated and attributed to outcome measures based on primary articles evaluating the efficacy of tES. These were then corresponded to a desired Jack-Bondi classification. A better understanding of the efficacy of tES on specific brain regions in synergy with diagnostic criteria will allow for standardization of treatment across all individuals impacted by MCI and Alzheimer’s pathology. This review suggests tES is ready to be brought out of an experimental phase, and can be used to guide new standards of care in the MCI patient population.

Keywords

MCI, tES, transcranial stimulation, mild cognitive impairment, Alzheimer Disease, Cognitive Decline, Transcranial Electrical Stimulation, Cognitive Dysfunction

Disciplines

Investigative Techniques | Medicine and Health Sciences | Nervous System Diseases | Neurology | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Pathological Conditions, Signs and Symptoms

Document Type

Poster

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May 2nd, 12:00 AM

Transcranial Electrical Stimulation as a Treatment for Aging-Related Cognitive Disorders: Review of Published Evidence

Alzheimer's disease (AD) and MCI are a major concern in modern neuropsychiatric care, chiefly for their difficult management. This strategic literature review categorizes MCI via the Jak-Bondi criteria and relates it to tES treatment paradigms. Commonly used outcome measures and regional brain mapping data synergizes associations between MCI pathology and potential tES treatment targets. Effect sizes were calculated and attributed to outcome measures based on primary articles evaluating the efficacy of tES. These were then corresponded to a desired Jack-Bondi classification. A better understanding of the efficacy of tES on specific brain regions in synergy with diagnostic criteria will allow for standardization of treatment across all individuals impacted by MCI and Alzheimer’s pathology. This review suggests tES is ready to be brought out of an experimental phase, and can be used to guide new standards of care in the MCI patient population.

 

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