Date of Presentation
5-2-2024 12:00 AM
College
Rowan-Virtua School of Osteopathic Medicine
Poster Abstract
Introduction: There is limited data about sex differences in patients undergoing a thoracic endovascular aortic repair (TEVAR) procedure. This study sought to examine the national inpatient sample (NIS) database to describe in-hospital outcomes by gender.
Methods: The NIS was searched for hospitalizations of adult patients who underwent TEVAR in 2019 and 2020. For this cohort, female patients were identified, and pregnant patients were excluded. The primary outcome was inpatient mortality. Secondary outcomes included hospital length of stay (LOS), and total hospital charges (TOTHCG).
Results: This study included 696 patients who underwent TEVAR. 255 (36.6%) females were identified, of which, 7 were pregnant and excluded from the study. Female patients who underwent TEVAR had higher prevalence of obesity (30.6% vs. 24.3%, p <0.001), smoking (28.1% vs. 22.3%, p <0.001), and CKD (5.2% vs. 4.2%, p <0.001). In-hospital mortality was higher among the female cohort (6.1% vs. 4.0%, p < 0.001). On multivariable regression, females who underwent TEVAR were associated with higher odds of inpatient mortality (OR 1.210, 95% CI 1.091-1.342, p <0.001). Additionally, patients who underwent TEVAR and had ventricular arrythmias pay significantly more TOTHCG ($600,004 vs. $462,216, P<0.001) with longer LOS (23.5days vs. 15.7days, p <0.001). On secondary analysis it has shown patients with ventricular arrhythmias who underwent TEVAR had higher odds of having acute kidney injury, developing shock, arrhythmias and congestive heart failure exacerbation.
Conclusion: In this nationally representative population‐based retrospective cohort study, female patients were associated with higher mortality and worse outcomes among patients undergoing TEVAR procedure.
Keywords
TEVAR, NIS, hospital mortality, female, Endovascular Aneurysm Repair, national inpatient sample, treatment outcome
Disciplines
Cardiology | Cardiovascular Diseases | Health Services Research | Medicine and Health Sciences | Patient Safety | Surgery | Surgical Procedures, Operative | Therapeutics
Document Type
Poster
Included in
Cardiology Commons, Cardiovascular Diseases Commons, Health Services Research Commons, Patient Safety Commons, Surgery Commons, Surgical Procedures, Operative Commons, Therapeutics Commons
Sex Differences in Outcomes Among Patients Undergoing Thoracic Endovascular Aortic Repair (TEVAR) Procedure: A Retrospective Cohort Study
Introduction: There is limited data about sex differences in patients undergoing a thoracic endovascular aortic repair (TEVAR) procedure. This study sought to examine the national inpatient sample (NIS) database to describe in-hospital outcomes by gender.
Methods: The NIS was searched for hospitalizations of adult patients who underwent TEVAR in 2019 and 2020. For this cohort, female patients were identified, and pregnant patients were excluded. The primary outcome was inpatient mortality. Secondary outcomes included hospital length of stay (LOS), and total hospital charges (TOTHCG).
Results: This study included 696 patients who underwent TEVAR. 255 (36.6%) females were identified, of which, 7 were pregnant and excluded from the study. Female patients who underwent TEVAR had higher prevalence of obesity (30.6% vs. 24.3%, p <0.001), smoking (28.1% vs. 22.3%, p <0.001), and CKD (5.2% vs. 4.2%, p <0.001). In-hospital mortality was higher among the female cohort (6.1% vs. 4.0%, p < 0.001). On multivariable regression, females who underwent TEVAR were associated with higher odds of inpatient mortality (OR 1.210, 95% CI 1.091-1.342, p <0.001). Additionally, patients who underwent TEVAR and had ventricular arrythmias pay significantly more TOTHCG ($600,004 vs. $462,216, P<0.001) with longer LOS (23.5days vs. 15.7days, p <0.001). On secondary analysis it has shown patients with ventricular arrhythmias who underwent TEVAR had higher odds of having acute kidney injury, developing shock, arrhythmias and congestive heart failure exacerbation.
Conclusion: In this nationally representative population‐based retrospective cohort study, female patients were associated with higher mortality and worse outcomes among patients undergoing TEVAR procedure.