Date of Presentation
5-2-2024 12:00 AM
College
Rowan-Virtua School of Osteopathic Medicine
Poster Abstract
Purpose: The purpose of this study is to compare pharmacologic intervention, neurocognitive therapy, physical therapy, and orthotics in treating the hypermobility subtype of Ehlers-Danlos Syndrome (hEDS) and determine which has the most positive effect on symptoms.
Introduction: Ehlers-Danlos Syndrome is an inheritable connective tissue disorder which results from a genetic mutation that alters the body’s ability to produce collagen. The most common subtype of Ehlers-Danlos Syndrome is hEDS, which leads to hypermobility and hyperextensibility and can cause frequent joint dislocations.
Methods: A review of literature was performed to compare each treatment based on reported results. The types of studies reviewed include systematic reviews, randomized clinical trials, review articles, cross sectional studies, and longitudinal studies. This study includes patients diagnosed with hEDS.
Results: Data was analyzed from different studies and presented using various figures and tables to compare the effectiveness of each treatment modality.
Discussion: Pain medications such as opioids and NSAIDs are the most commonly used treatment option, but they carry the risk of addiction and other side effects. Use of orthotics was the most successful treatment option in alleviating symptoms of hEDS.
Conclusion: Pharmacologic intervention, neurocognitive therapy, physical therapy, and orthotics each have their own benefits in treating hEDS. Therefore, a combination of each therapy should be used to ensure the greatest positive effect on the symptoms of hEDS. Future research should focus on more direct comparisons of each treatment method to identify which modality consistently yields the best results.
Keywords
Ehlers-Danlos Syndrome, joint hypermobility, Treatment Outcome, pain medication, opioids, chronic pain, Pain Management
Disciplines
Cognitive Behavioral Therapy | Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Health and Medical Administration | Medicine and Health Sciences | Orthotics and Prosthetics | Other Analytical, Diagnostic and Therapeutic Techniques and Equipment | Pathological Conditions, Signs and Symptoms | Physical Therapy | Physiotherapy | Rheumatology | Skin and Connective Tissue Diseases | Therapeutics
Document Type
Poster
Included in
Cognitive Behavioral Therapy Commons, Congenital, Hereditary, and Neonatal Diseases and Abnormalities Commons, Health and Medical Administration Commons, Orthotics and Prosthetics Commons, Other Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons, Pathological Conditions, Signs and Symptoms Commons, Physical Therapy Commons, Physiotherapy Commons, Rheumatology Commons, Skin and Connective Tissue Diseases Commons, Therapeutics Commons
A Literature Review of Current Treatments for the Hypermobility Subtype of Ehlers-Danlos Syndrome
Purpose: The purpose of this study is to compare pharmacologic intervention, neurocognitive therapy, physical therapy, and orthotics in treating the hypermobility subtype of Ehlers-Danlos Syndrome (hEDS) and determine which has the most positive effect on symptoms.
Introduction: Ehlers-Danlos Syndrome is an inheritable connective tissue disorder which results from a genetic mutation that alters the body’s ability to produce collagen. The most common subtype of Ehlers-Danlos Syndrome is hEDS, which leads to hypermobility and hyperextensibility and can cause frequent joint dislocations.
Methods: A review of literature was performed to compare each treatment based on reported results. The types of studies reviewed include systematic reviews, randomized clinical trials, review articles, cross sectional studies, and longitudinal studies. This study includes patients diagnosed with hEDS.
Results: Data was analyzed from different studies and presented using various figures and tables to compare the effectiveness of each treatment modality.
Discussion: Pain medications such as opioids and NSAIDs are the most commonly used treatment option, but they carry the risk of addiction and other side effects. Use of orthotics was the most successful treatment option in alleviating symptoms of hEDS.
Conclusion: Pharmacologic intervention, neurocognitive therapy, physical therapy, and orthotics each have their own benefits in treating hEDS. Therefore, a combination of each therapy should be used to ensure the greatest positive effect on the symptoms of hEDS. Future research should focus on more direct comparisons of each treatment method to identify which modality consistently yields the best results.