Date of Presentation
5-2-2024 12:00 AM
College
Rowan-Virtua School of Osteopathic Medicine
Poster Abstract
We report a case of a 54-year-old female who presented with mild shortness of breath, lower chest discomfort, fatigue, and weakness ongoing for several days and was diagnosed with thrombotic thrombocytopenic purpura (TTP). TTP is characterized by microangiopathic hemolytic anemia and thrombocytopenia due to either an inherited or immune-mediated reduction in von Willebrand Factor (VWF) cleaving protease ADAMTS13.
Patients presenting with non-specific symptoms is becoming increasingly common and initial bias could be to attribute symptoms to viral syndrome or upper respiratory tract infection. However, the differential for non-specific complaints is extensive and thorough review of labs and re-evaluations of patients is important for discovering other potentially medically emergent causes of symptoms including TTP.
Keywords
Thrombotic Thrombocytopenic Purpura, ADAMTS13 Protein, Hemolytic Anemia, Thrombocytopenia, Physical Examination, Differential Diagnosis
Disciplines
Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Diagnosis | Emergency Medicine | Hematology | Hemic and Lymphatic Diseases | Medicine and Health Sciences | Other Public Health | Pathological Conditions, Signs and Symptoms | Quality Improvement
Document Type
Poster
Included in
Congenital, Hereditary, and Neonatal Diseases and Abnormalities Commons, Diagnosis Commons, Emergency Medicine Commons, Hematology Commons, Hemic and Lymphatic Diseases Commons, Other Public Health Commons, Pathological Conditions, Signs and Symptoms Commons, Quality Improvement Commons
Case Report: A Case of TTP in the ED
We report a case of a 54-year-old female who presented with mild shortness of breath, lower chest discomfort, fatigue, and weakness ongoing for several days and was diagnosed with thrombotic thrombocytopenic purpura (TTP). TTP is characterized by microangiopathic hemolytic anemia and thrombocytopenia due to either an inherited or immune-mediated reduction in von Willebrand Factor (VWF) cleaving protease ADAMTS13.
Patients presenting with non-specific symptoms is becoming increasingly common and initial bias could be to attribute symptoms to viral syndrome or upper respiratory tract infection. However, the differential for non-specific complaints is extensive and thorough review of labs and re-evaluations of patients is important for discovering other potentially medically emergent causes of symptoms including TTP.