Rowan Digital Works

The Ig heavy chain intronic enhancer core region is necessary and sufficient to promote efficient class switch recombination., Eiko Sakai, Andrea Bottaro, Frederick W. Alt
Andrea Bottaro

Discordance between IgA switching at the DNA level and IgA expression at the mRNA level in IgA-deficient patients., Zhigang Wang, David Yunis, Macarena Irigoyen, Betsy Kitchens, Andrea Bottaro, Frederick W. Alt, Chester A. Alper
Andrea Bottaro

Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus, Katherine J. Seidl, John P. Manis, Andrea Bottaro, Jue Zhang, Laurie Davidson, Alison Kisselgof, Hans Oettgen, Frederick W. Alt
Andrea Bottaro

Recombination and transcription of the endogenous Ig heavy chain locus is effected by the Ig heavy chain intronic enhancer core region in the absence of the matrix attachment regions, Eiko Sakai, Andrea Bottaro, Laurie Davidson, Barry P. Sleckman, Frederick W. Alt
Andrea Bottaro

An expressed neo(r) cassette provides required functions of the 1gamma2b exon for class switching., Katherine J. Seidl, Andrea Bottaro, Annie Vo, Jue Zhang, Laurie Davidson, Frederick W. Alt
Andrea Bottaro

Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus., Andrea Bottaro, Faith Young, Jianzhu Chen, Matthias Serwe, Fred Sablitzky, Frederick W. Alt
Andrea Bottaro

CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation., Emanuela Castigli, Frederick W. Alt, Laurie Davidson, Andrea Bottaro, Emiko Mizoguchi, Atul K. Bhan, Raif S. Geha
Andrea Bottaro

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus, Michel Cogné, Michel Cogné, Rusty Lansford, Andrea Bottaro, Andrea Bottaro, Jue Zhang, James Gorman, Faith Young, Hwel-Ling Cheng, Frederick W. Alt
Andrea Bottaro

S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process., Andrea Bottaro, Rusty Lansford, Lixing Xu, Jue Zhang, Paul Rothman, Frederick W. Alt
Andrea Bottaro

Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching., Lixing Xu, Beverly Gorham, Suzanne C. Li, Andrea Bottaro, Frederick W. Alt, Paul Rothman
Andrea Bottaro