Part of the Biochemistry, Biophysics, and Structural Biology Commons

Works by Manoj K. Pandey in Biochemistry, Biophysics, and Structural Biology

2018

Design and synthesis of novel thiobarbituric acid derivatives targeting both wild-type and BRAF-mutated melanoma cells, Srinivasa Rao Ramisetti, Manoj K. Pandey, Sang Y. Lee, Deepkamal Karelia, Satya Narayan, Shantu Amin, Arun K. Sharma
Manoj Pandey

2017

Design, synthesis, and identification of a novel napthalamide-isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti-melanoma activity, Deepkamal N. Karelia, Ugir Hossain Sk, Parvesh Singh, A.S. Prakasha Gowda, Manoj K. Pandey, Srinivasa R. Ramisetti, Shantu Amin, Arun K. Sharma
Manoj Pandey

2016

Abstract 4732: A novel analog of Leonurine inhibits melanoma growth and survival through STAT3 signaling pathways, Manoj K. Pandey, Jacek Krzeminski, Deepkamal Karelia, Arun K. Sharma, Shantu G. Amin
Manoj Pandey

Abstract 3061: AS-10: a new small molecule with promising activity against pancreatic cancer, Deepkamal Karelia, Manoj K. Pandey, Daniel Plano, Shantu Amin, Arun K. Sharma
Manoj Pandey

Abstract 3067: A novel tamoxifen analog, GA-11, as potential breast cancer therapeutic, Gurleen Kaur, Mohinder P. Mahajan, Manoj K. Pandey, Parvesh Singh, Srinivasa R. Ramisetti, Arun K. Sharma
Manoj Pandey

Design, synthesis, and anti-breast cancer evaluation of new triarylethylene analogs bearing short alkyl- and polar amino-/amido-ethyl chains., Gurleen Kaur, Mohinder P. Mahajan, Manoj K. Pandey, Parvesh Singh, Srinivasa R. Ramisetti, Arun K. Sharma
Manoj Pandey

2015

Abstract 2734: Ethanol potentiates tobacco smoke carcinogens-induced MAPK activation, Manoj K. Pandey, Jagat J. Mukherjee, Dhimant H. Desai, Shantu G. Amin, Subodh Kumar
Manoj Pandey

2014

Abstract 2139: Pre-clinical chemopreventive efficacy of a novel hybrid p-XSC-aspirin compound in a NNK-induced A/J mouse lung cancer model, Daniel Plano, Cesar Aliaga, Manoj K. Pandey, Arunangshu Das, Timothy K. Cooper, Shantu Amin, Arun K. Sharma
Manoj Pandey

Abstract 4204: Isatin analog as bruton tyrosine kinase inhibitor: A promising novel agent for multiple myeloma treatment, Krishne Gowda, Manoj K. Pandey, Arun K. Sharma, Shantu Amin
Manoj Pandey

Abstract 1639: Development of novel thiobarbituric acid derivatives as potential cancer therapeutics, Srinivasa R. Ramisetti, Sang Y. Lee, Manoj K. Pandey, Shantu G. Amin, Arun K. Sharma
Manoj Pandey

Abstract 3786: Gambogic acid inhibits chemokine receptor CXCR4 signaling pathways and osteoclastogenesis in multiple myeloma, Manoj K. Pandey, Vijay P. Kale, Chunhua Song, Shen-shu Sung, Arun K. Sharma, Sinisa Dovat, Shantu G. Amin
Manoj Pandey

Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways, Manoj K. Pandey, Vijay P. Kale, Chunhua Song, Shen-shu Sung, Arun K. Sharma, Giampaolo Talamo, Sinisa Dovat, Shantu G. Amin
Manoj Pandey

Design, synthesis and evaluation of Ospemifene analogs as anti-breast cancer agents., Gurleen Kaur, Mohinder P. Mahajan, Manoj K. Pandey, Parvesh Singh, Srinivasa R. Ramisetti, Arun K. Sharma
Manoj Pandey

2013

Proteasomal degradation of Mcl-1 by maritoclax induces apoptosis and enhances the efficacy of ABT-737 in melanoma cells., Manoj K. Pandey, Krishne Gowda, Kenichiro Doi, Arun K. Sharma, Hong-Gang Wang, Shantu Amin
Manoj Pandey

2012

Knockdown of c-Fos suppresses the growth of human colon carcinoma cells in athymic mice, Manoj K. Pandey, Guangming Liu, Timothy K. Cooper, Kathleen M. Mulder
Manoj Pandey

Phenylalkyl isoselenocyanates vs phenylalkyl isothiocyanates: thiol reactivity and its implications., Melissa A. Crampsie, Manoj K. Pandey, Dhimant Desai, Julian Spallholz, Shantu Amin, Arun K. Sharma
Manoj Pandey

2011

Gambogic Acid Inhibits STAT3 Phosphorylation through Activation of Protein Tyrosine Phosphatase SHP-1: Potential Role in Proliferation and Apoptosis, Sahdeo Prasad, Manoj K. Pandey, Vivek R. Yadav, Bharat B. Aggarwal
Manoj Pandey

2010

Escin, a Pentacyclic Triterpene, Chemosensitizes Human Tumor Cells through Inhibition of Nuclear Factor-κB Signaling Pathway, Kuzhuvelil B. Harikumar, Bokyung Sung, Manoj K. Pandey, Sushovan Guha, Sunil Krishnan, Bharat B. Aggarwal
Manoj Pandey

5-Hydroxy-2-Methyl-1,4-Naphthoquinone, a Vitamin K3 Analogue, Suppresses STAT3 Activation Pathway through Induction of Protein Tyrosine Phosphatase, SHP-1: Potential Role in Chemosensitization, Santosh K. Sandur, Manoj K. Pandey, Bokyung Sung, Bharat B. Aggarwal
Manoj Pandey

Betulinic Acid Suppresses STAT3 Activation Pathway Through Induction of Protein Tyrosine Phosphatase SHP-1 in Human Multiple Myeloma Cells, Manoj K. Pandey, Bokyung Sung, Bharat B. Aggarwal
Manoj Pandey

Sesamin Manifests Chemopreventive Effects through the Suppression of NF-κB-Regulated Cell Survival, Proliferation, Invasion, and Angiogenic Gene Products, Kuzhuvelil B. Harikumar, Bokyung Sung, Sheeja T. Tharakan, Manoj K. Pandey, Beena Joy, Sushovan Guha, Sunil Krishnan, Bharat B. Aggarwal
Manoj Pandey

2008

EWS-FLI1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse model., Patrick P. Lin, Manoj K. Pandey, Fenghua Jin, Shunbin Xiong, Michael Deavers, John M. Parant, Guillermina Lozano
Manoj Pandey

Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-κB–regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-κBα kinase, leading to potentiation of apoptosis, Bokyung Sung, Manoj K. Pandey, Kwang Seok Ahn, Tingfang Yi, Madan M. Chaturvedi, Mingyao Liu, Bharat B. Aggarwal
Manoj Pandey

2007

Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane)., Santosh K. Sandur, Haruyo Ichikawa, Manoj K. Pandey, Ajaikumar B. Kunnumakkara, Bokyung Sung, Gautam Sethi, Bharat B. Aggarwal
Manoj Pandey

Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-κB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis, Ajaikumar B. Kunnumakkara, Asha S. Nair, Kwang Seok Ahn, Manoj K. Pandey, Zhengfang Yi, Mingyao Liu, Bharat B. Aggarwal
Manoj Pandey

Fisetin, an Inhibitor of Cyclin-Dependent Kinase 6, Down-Regulates Nuclear Factor-κB-Regulated Cell Proliferation, Antiapoptotic and Metastatic Gene Products through the Suppression of TAK-1 and Receptor-Interacting Protein-Regulated IκBα Kinase Activation, Bokyung Sung, Manoj K. Pandey, Bharat B. Aggarwal
Manoj Pandey

Natural products as a gold mine for arthritis treatment, Dinesh Khanna, Gautam Sethi, Kwang Seok Ahn, Manoj K. Pandey, Ajaikumar B. Kunnumakkara, Bokyung Sung, Amita Aggarwal, Bharat B. Aggarwal
Manoj Pandey

2006

Induction of hepatic cytochrome P450 isozymes, benzo(a)pyrene metabolism and DNA binding following exposure to polycyclic aromatic hydrocarbon residues generated during repeated fish fried oil in rats., Manoj K. Pandey, Sanjay Yadav, Devendra Parmar, Mukul Das
Manoj Pandey

In vitro cytotoxicity of polycyclic aromatic hydrocarbon residues arising through repeated fish fried oil in human hepatoma Hep G2 cell line, Manoj K. Pandey, Aditya B. Pant, Mukul Das
Manoj Pandey

Assessment of carcinogenic potential of repeated fish fried oil in mice., Manoj K. Pandey, Mukul Das
Manoj Pandey

Induction of P53, P21Waf1, orinithine decorboxylase activity, and DNA damage leading to cell-cycle arrest and apoptosis following topical application of repeated fish fried oil extract to mice, Manoj K. Pandey, Alok Dhawan, Mukul Das
Manoj Pandey

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution., Bharat B. Aggarwal, Gautam Sethi, Kwang Seok Ahn, Santosh K. Sandur, Manoj K. Pandey, Ajaikumar B. Kunnumakkara, Bokyung Sung, Haruyo Ichikawa
Manoj Pandey