Changes in the expression and function of the PDE5 pathway in the obstructed urinary bladder
Michael DiSanto
Part of the Physiology Commons
Works by Michael E. DiSanto in Physiology
2020
Alterations in the phosphodiesterase type 5 pathway and oxidative stress correlate with erectile function in spontaneously hypertensive rats.
Michael DiSanto
2018
Testosterone regulates myosin II isoforms expression and functional activity in the rat prostate.
Michael DiSanto
Testosterone regulates the expression and functional activity of sphingosine-1-phosphate receptors in the rat corpus cavernosum.
Michael DiSanto
2017
The expression and functional activities of smooth muscle myosin and non-muscle myosin isoforms in rat prostate
Michael DiSanto
2016
AB302. SPR-29 Sphingosine-1-phosphate in vitro and in vivo modulates corpus cavernosum smooth muscle tone
Michael DiSanto
2015
Basic Science Evidence for the Link Between Erectile Dysfunction and Cardiometabolic Dysfunction
Michael DiSanto
2012
Smooth muscle myosin expression, isoform composition, and functional activities in rat corpus cavernosum altered by the streptozotocin-induced type 1 diabetes
Michael DiSanto
Large-conductance calcium-activated potassium channel activity, as determined by whole-cell patch clamp recording, is decreased in urinary bladder smooth muscle cells from male rats with partial urethral obstruction.
Michael DiSanto
Testosterone regulates smooth muscle contractile pathways in the rat prostate: emphasis on PDE5 signaling.
Michael DiSanto
2011
Blebbistain, a myosin II inhibitor, as a novel strategy to regulate detrusor contractility in a rat model of partial bladder outlet obstruction.
Michael DiSanto
2010
The sphingosine-1-phosphate pathway is upregulated in response to partial urethral obstruction in male rats and activates RhoA/Rho-kinase signalling
Michael DiSanto
2009
Testosterone regulates erectile function and Vcsa1 expression in the corpora of rats
Michael DiSanto
EFFECT OF CAVERNOUS NEUROTOMY ON CORPUS CAVERNOSUM SMOOTH MUSCLE: ALTERATION IN MYOSIN ISOFORM COMPOSITION AND THE SPHINGOSINE-1-PHOSPHATE/RHO-KINASE SIGNALING PATHWAY
Michael DiSanto
LARGE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ACTIVITY, AS DETERMINED BY WHOLE CELL PATCH CLAMP RECORDING, IS DECREASED IN URINARY BLADDER SMOOTH MUSCLE CELLS FROM MALE RATS WITH PARTIAL URETHRAL OBSTRUCTION
Michael DiSanto
SPHINGOSINE-1-PHOSPHATE INDUCED CONTRACTION OF HUMAN CORPUS CAVERNOSUM SMOOTH MUSCLE IS MEDIATED BY THE RHO-KINASE PATHWAY AND IS UPREGULATED BY DIABETES, WHILE IN VIVO ADMINISTRATION OF JTE-013 (A SELECTIVE S1P2 RECEPTOR ANTAGONIST) INCREASES INTRACAVERNOUS PRESSURE
Michael DiSanto
Regional heterogeneity in expression of the sphingosine-1-phosphate pathway in the female rat lower urinary tract.
Michael DiSanto
In Vitro and In Vivo Relaxation of Corpus Cavernosum Smooth Muscle by the Selective Myosin II Inhibitor, Blebbistatin
Michael DiSanto
2008
SPHINGOSINE-1-PHOSPHATE (S1P) SIGNALING PATHWAY IN DIABETES-INDUCED ERECTILE DYSFUNCTION (ED): POTENTIAL FOR S1P AS A BIOMARKER OF DIABETES- INDUCED ED
Michael DiSanto
2007
980: The FVB-OB/OB Mouse: A Model for Voiding Dysfunction Associated with Type II Diabetes Exhibiting Decreased Expression of Endothelin A Receptor
Michael DiSanto
2006
Activation of the Calcineurin Pathway is Associated With Detrusor Decompensation: A Potential Therapeutic Target
Michael DiSanto
Partial Bladder Outlet Obstruction Induces Urethral Smooth Muscle Hypertrophy and Decreased Force Generation
Michael DiSanto
Altered expression of thin filament-associated proteins in hypertrophied urinary bladder smooth muscle.
Michael DiSanto
2005
Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase beta and CPI-17.
Michael DiSanto
Increased corpus cavernosum smooth muscle tone associated with partial bladder outlet obstruction is mediated via Rho-kinase
Michael DiSanto
161: Diabetes-Induced Increase in Detrusor Smooth Muscle Myosin Basal Phosphorylation Level is Associated with an Upregulation of Rho-Kinase and CPI-17
Michael DiSanto
2004
Downregulation of cGMP-dependent protein kinase-1 activity in the corpus cavernosum smooth muscle of diabetic rabbits
Michael DiSanto
1416: Decreased CGMP-Dependent Protein Kinase-1 (PKG-1) Expression and Activity in the Corpus Cavernosum of Alloxan-Induced Diabetic Rabbits
Michael DiSanto
1617: Alterations in the Expression of Enzymes that Modulate Corpus Ca Vernosum Smooth Muscle Contraction in Men with Erectile Dysfunction
Michael DiSanto
2003
Alteration in expression of myosin isoforms in detrusor smooth muscle following bladder outlet obstruction
Michael DiSanto
Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase
Michael DiSanto
2002
Generation of a cell line with smooth muscle phenotype from hypertrophied urinary bladder
Michael DiSanto
2000
1999
Myosin light chain phosphorylation at resting level and the composition of myosin isoforms in the bladder body and urethra.
Michael DiSanto
DO ALTERATIONS IN THE COMPOSITION OF ISOFORMS OF MYOSIN, THE MOLECULAR MOTOR FOR MUSCLE CONTRACTION, IN AGING CORPORA CAVERNOSA FAVOR CONTRACTION OVER RELAXATION?
Michael DiSanto
Pro-inflammatory cytokines induce expression of matrix-metabolizing enzymes in human cervical smooth muscle cells
Michael DiSanto
