Part of the Physiology Commons

Works by Samuel Chacko in Physiology

2006

Partial Bladder Outlet Obstruction Induces Urethral Smooth Muscle Hypertrophy and Decreased Force Generation, Joseph A. Hypolite, Shaohua Chang, Yongmu Zheng, Michael E. DiSanto, Stephen A. Zderic, Alan J. Wein, Samuel Chacko
Michael DiSanto

Altered expression of thin filament-associated proteins in hypertrophied urinary bladder smooth muscle., Anita S. Mannikarottu, Michael E. DiSanto, Stephen A. Zderic, Alan J. Wein, Samuel Chacko
Michael DiSanto

2005

Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase beta and CPI-17., Shaohua Chang, Joseph A. Hypolite, Michael E. DiSanto, Arun Changolkar, Alan J. Wein, Samuel Chacko
Michael DiSanto

Increased corpus cavernosum smooth muscle tone associated with partial bladder outlet obstruction is mediated via Rho-kinase, Shaohua Chang, Joseph A. Hypolite, Stephen A. Zderic, Alan J. Wein, Samuel Chacko, Michael E. DiSanto
Michael DiSanto

161: Diabetes-Induced Increase in Detrusor Smooth Muscle Myosin Basal Phosphorylation Level is Associated with an Upregulation of Rho-Kinase and CPI-17, Shaohua Chang, Joseph A. Hypolite, Arun Changolkar, Michael E. DiSanto, Alan J. Wein, Samuel Chacko
Michael DiSanto

DIABETES INDUCED DECREASE IN DETRUSOR SMOOTH MUSCLE FORCE IS ASSOCIATED WITH OXIDATIVE STRESS AND OVERACTIVITY OF ALDOSE REDUCTASE, Arun K. Changolkar, Joseph A. Hypolite, Michael Disanto, Peter J. Oates, Alan J. Wein, Samuel Chacko
Michael DiSanto

REGIONAL ALTERATIONS IN THE EXPRESSION OF SMOOTH MUSCLE MYOSIN ISOFORMS IN RESPONSE TO PARTIAL BLADDER OUTLET OBSTRUCTION, Anita S. Mannikarottu, Joseph A. Hypolite, Stephen A. Zderic, Alan J. Wein, Samuel Chacko, Michael E. Disanto
Michael DiSanto

2004

Over expression of smooth muscle specific caldesmon by transfection and intermittent agonist induced contraction alters cellular morphology and restores differentiated smooth muscle phenotype., Aseem R. Shukla, Trang Nguyen, Yongmu Zheng, Stephen A. Zderic, Michael DiSANTO, Alan J. Wein, Samuel Chacko
Michael DiSanto

Downregulation of cGMP-dependent protein kinase-1 activity in the corpus cavernosum smooth muscle of diabetic rabbits, Shaohua Chang, Joseph A. Hypolite, Marielena Velez, Arun Changolkar, Alan J. Wein, Samuel Chacko, Michael E. DiSanto
Michael DiSanto

1416: Decreased CGMP-Dependent Protein Kinase-1 (PKG-1) Expression and Activity in the Corpus Cavernosum of Alloxan-Induced Diabetic Rabbits, Shaohua Chang, Joseph A. Hypolite, Arun K. Changolkar, Alan J. Wein, Samuel Chacko, Michael E. DiSanto
Michael DiSanto

1617: Alterations in the Expression of Enzymes that Modulate Corpus Ca Vernosum Smooth Muscle Contraction in Men with Erectile Dysfunction, Shaohua Chang, Terrence R. Malloy, Stanley B. Malkowicz, Alan J. Wein, Samuel Chacko, Michael E. DiSanto
Michael DiSanto

Alteration of contractile and regulatory proteins following partial bladder outlet obstruction., Samuel Chacko, Shaohua Chang, Joseph A. Hypolite, Michael E. Disanto, Alan J. Wein
Michael DiSanto

2003

Alteration in expression of myosin isoforms in detrusor smooth muscle following bladder outlet obstruction, Michael E. DiSanto, Raimund Stein, Shaohua Chang, Joseph A. Hypolite, Yongmu Zheng, Stephen Zderic, Alan J. Wein, Samuel Chacko
Michael DiSanto

Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase, Wu Bing, Shaohua Chang, Joseph A. Hypolite, Michael E. DiSanto, Stephen A. Zderic, Lester Rolf, Alan J. Wein, Samuel Chacko
Michael DiSanto

2002

Generation of a cell line with smooth muscle phenotype from hypertrophied urinary bladder, Yongmu Zheng, Wilfried T. Weber, Shuqin Wang, Alan J. Wein, Stephen A. Zderic, Samuel Chacko, Michael E. DiSanto
Michael DiSanto

Enhanced Force Generation by Corpus Cavernosum Smooth Muscle in Rabbits With Partial Bladder Outlet Obstruction, Shaohua Chang, Joseph A. Hypolite, Stephen A. Zderic, Alan J. Wein, Samuel Chacko, Michael E. DiSANTO
Michael DiSanto

2001

Estrogen modulates the expression of myosin heavy chain in detrusor smooth muscle., Ricardo F. Sanchez-Ortiz, Z. E. Wang, Chandrakala Menon, Michael E. Disanto, Alan J. Wein, Samuel Chacko
Michael DiSanto

2000

Lower urinary tract physiology and pharmacology, Michael E. DiSanto, Alan J. Wein, Samuel Chacko
Michael DiSanto

Improved contractility of obstructed bladders after tadenan treatment is associated with reversal of altered myosin isoform expression, Cristiano M. Gomes, Michael E. Disanto, Patrick Horan, Robert M. Levin, Alan J. Wein, Samuel Chacko
Michael DiSanto

1999

Myosin light chain phosphorylation at resting level and the composition of myosin isoforms in the bladder body and urethra., Joseph A. Hypolite, Michael E. DiSanto, Alan J. Wein, Samuel Chacko
Michael DiSanto

DO ALTERATIONS IN THE COMPOSITION OF ISOFORMS OF MYOSIN, THE MOLECULAR MOTOR FOR MUSCLE CONTRACTION, IN AGING CORPORA CAVERNOSA FAVOR CONTRACTION OVER RELAXATION?, Michael E. DiSanto, Gregory A. Broderick, Joseph A. Hypolite, Yongmu Zheng, Alan J. Wien, Samuel Chacko
Michael DiSanto

Pro-inflammatory cytokines induce expression of matrix-metabolizing enzymes in human cervical smooth muscle cells, Michiko Watari, Hidemichi Watari, Michael E. DiSanto, Samuel Chacko, Guo-Ping Shi, Jerome F. Strauss
Michael DiSanto

1998

Expression of myosin isoforms in smooth muscle cells in the corpus cavernosum penis, Michael E. DiSanto, Ze Wang, Chandrakala Menon, Yongmu Zheng, Thomas Chacko, Joseph Hypolite, Gregory Broderick, Alan J. Wein, Samuel Chacko
Michael DiSanto