Date of Presentation

5-3-2018 8:00 AM

College

School of Osteopathic Medicine

Poster Abstract

Precedex is an intravenous, α-2 receptor agonist broadly used for analgesia, maintenance of sedation, and alcohol withdrawal treatment in the intensive care unit (ICU).

The most commonly reported adverse effects associated with precedex are hypotension and bradycardia1.

Fever has been reported with a 5-7% incidence rate. Our case shows a very impressive pyrexia in a 49 year old patient most likely associated to Precedex. When compared to the previously three reported cases his fever reached the largest value (T= 107ºF).

As its use becomes more and more common in the ICU, clinicians should be aware of this adverse effect especially in patients whose fevers are refractory to acetaminophen and temperatures that are higher than 104ºF.

Keywords

dexmedetomidine, fever, Drug-Related Side Effects and Adverse Reactions

Disciplines

Anesthesia and Analgesia | Medicine and Health Sciences | Pharmaceutical Preparations

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May 3rd, 8:00 AM

Dexmedetomidine (Precedex) Induced Fever

Precedex is an intravenous, α-2 receptor agonist broadly used for analgesia, maintenance of sedation, and alcohol withdrawal treatment in the intensive care unit (ICU).

The most commonly reported adverse effects associated with precedex are hypotension and bradycardia1.

Fever has been reported with a 5-7% incidence rate. Our case shows a very impressive pyrexia in a 49 year old patient most likely associated to Precedex. When compared to the previously three reported cases his fever reached the largest value (T= 107ºF).

As its use becomes more and more common in the ICU, clinicians should be aware of this adverse effect especially in patients whose fevers are refractory to acetaminophen and temperatures that are higher than 104ºF.

 

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