Date of Presentation
5-2-2019 12:00 AM
College
School of Osteopathic Medicine
Poster Abstract
Background: Pregnancy is associated with an increased risk of stroke in young women. Idiopathic moyamoya syndrome (IMMS) is a rare condition characterized by progressive narrowing of large cerebral arteries resulting in flimsy collaterals prone to rupture or thrombosis. Data are limited on pregnancy outcomes in women with IMMS. We hypothesized that IMMS would be associated with increased pregnancy morbidity, including stroke.
Conclusion: Pregnancies within 1 year prior or any time after IMMS diagnosis did not have increased maternal morbidity compared to unexposed pregnancies after adjusting for age and clustering of women with multiple pregnancies. Prospective studies are needed to better characterize increased maternal risks for women with moyamoya syndrome and develop preventive strategies.
Keywords
Moyamoya syndrome, pregnancy, stroke, maternal morbidity
Disciplines
Cardiovascular Diseases | Medicine and Health Sciences | Neurology | Obstetrics and Gynecology | Women's Health
Document Type
Poster
Included in
Cardiovascular Diseases Commons, Neurology Commons, Obstetrics and Gynecology Commons, Women's Health Commons
Maternal Morbidity Outcomes in Idiopathic Moyamoya Syndrome in New York State
Background: Pregnancy is associated with an increased risk of stroke in young women. Idiopathic moyamoya syndrome (IMMS) is a rare condition characterized by progressive narrowing of large cerebral arteries resulting in flimsy collaterals prone to rupture or thrombosis. Data are limited on pregnancy outcomes in women with IMMS. We hypothesized that IMMS would be associated with increased pregnancy morbidity, including stroke.
Conclusion: Pregnancies within 1 year prior or any time after IMMS diagnosis did not have increased maternal morbidity compared to unexposed pregnancies after adjusting for age and clustering of women with multiple pregnancies. Prospective studies are needed to better characterize increased maternal risks for women with moyamoya syndrome and develop preventive strategies.