Date of Presentation
5-5-2022 12:00 AM
College
School of Osteopathic Medicine
Poster Abstract
Prostate cancer is the leading malignancy and third most common cause of cancer death among men. In the United States, racial disparities exist in prostate cancer incidence and mortality rates. According to the National Cancer Institute, African American (AA) men have a significantly increased incidence of prostate cancer compared to Caucasians or Asians. Urinary leak at the urethrovesical anastomosis has been cited as a complication of radical prostatectomy (RP), with incidence rates as high as 23%. Urinary anastomotic leak is associated with increased rates of ileus, prolonged hospitalization rates, and longer time to achieve continence. The etiology of risk factors in urinary anastomotic leak post RP is most likely multifactorial; however, the impact of racial disparities on incidence of urinary anastomotic leak has not been studied.
The objective of this study was to determine the impact of racial group on rates of urinary anastomotic leak in patients who have undergone RP for malignant neoplasm of the prostate. We predict that higher pathological staging and comorbid conditions contribute to urinary anastomotic leak in AAs. Secondary factors including postoperative complications were also examined to analyze their impact on urinary anastomotic leaks between racial groups.
Keywords
Male, United States, Anastomotic Leak, Prostate, Prostatectomy, Prostatic Neoplasms, Urinary Incontinence, Racial Groups
Disciplines
Male Urogenital Diseases | Medicine and Health Sciences | Neoplasms | Oncology | Surgery | Urogenital System | Urology
Document Type
Poster
Included in
Male Urogenital Diseases Commons, Neoplasms Commons, Oncology Commons, Surgery Commons, Urogenital System Commons, Urology Commons
The Impact of Racial Disparities and Outcomes on Urinary Anastomotic Leak in Radical Prostatectomy
Prostate cancer is the leading malignancy and third most common cause of cancer death among men. In the United States, racial disparities exist in prostate cancer incidence and mortality rates. According to the National Cancer Institute, African American (AA) men have a significantly increased incidence of prostate cancer compared to Caucasians or Asians. Urinary leak at the urethrovesical anastomosis has been cited as a complication of radical prostatectomy (RP), with incidence rates as high as 23%. Urinary anastomotic leak is associated with increased rates of ileus, prolonged hospitalization rates, and longer time to achieve continence. The etiology of risk factors in urinary anastomotic leak post RP is most likely multifactorial; however, the impact of racial disparities on incidence of urinary anastomotic leak has not been studied.
The objective of this study was to determine the impact of racial group on rates of urinary anastomotic leak in patients who have undergone RP for malignant neoplasm of the prostate. We predict that higher pathological staging and comorbid conditions contribute to urinary anastomotic leak in AAs. Secondary factors including postoperative complications were also examined to analyze their impact on urinary anastomotic leaks between racial groups.