Date of Presentation
5-4-2023 12:00 AM
College
School of Osteopathic Medicine
Poster Abstract
Parkinson’s disease (PD) is a neurodegenerative disorder that causes a variety of motor and non-motor symptoms. The goal of this project was to understand whether the weight loss seen with Parkinson’s disease was due to the lack of being able to access the food because of the food placement or because of inability to chew the food due to degeneration of muscles required for chewing food. Both treatment groups, Adjusted Diet and Unadjusted Diet, lost weight after injections started, whereas control weights were stable throughout the experiment. There is no statistically significant difference in weight loss between adjusted and unadjusted food groups. Because there were no statistically significant findings between the two groups (adjusted food vs. unadjusted food), the weight loss seen with Parkinson’s disease still needs to be explored.
Keywords
Parkinson Disease, Weight Loss, Body Weight, Animal Disease Models
Disciplines
Disease Modeling | Investigative Techniques | Medicine and Health Sciences | Nervous System Diseases | Pathological Conditions, Signs and Symptoms | Physiological Processes
Document Type
Poster
Included in
Disease Modeling Commons, Investigative Techniques Commons, Nervous System Diseases Commons, Pathological Conditions, Signs and Symptoms Commons, Physiological Processes Commons
The Role of Food Accessibility in Weight Loss in a Rat Model of Parkinson’s Disease
Parkinson’s disease (PD) is a neurodegenerative disorder that causes a variety of motor and non-motor symptoms. The goal of this project was to understand whether the weight loss seen with Parkinson’s disease was due to the lack of being able to access the food because of the food placement or because of inability to chew the food due to degeneration of muscles required for chewing food. Both treatment groups, Adjusted Diet and Unadjusted Diet, lost weight after injections started, whereas control weights were stable throughout the experiment. There is no statistically significant difference in weight loss between adjusted and unadjusted food groups. Because there were no statistically significant findings between the two groups (adjusted food vs. unadjusted food), the weight loss seen with Parkinson’s disease still needs to be explored.