Comparing Cognitive Tests and Smartphone-Based Assessment in 2 US Community-Based Cohorts.

Ileana De Anda-Duran
Preeti Sunderaraman
Edward Searls
Shirine Moukaled
Xuanyi Jin
Zachary Popp
Cody Karjadi
Phillip H Hwang
Huitong Ding
Sherral Devine
Ludy C Shih
Spencer Low
Honghuang Lin
Vijaya B Kolachalama
Lydia Bazzano
David J. Libon, Rowan University
Rhoda Au

Copyright © 2024 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License.

Abstract

BACKGROUND: Smartphone-based cognitive assessments have emerged as promising tools, bridging gaps in accessibility and reducing bias in Alzheimer disease and related dementia research. However, their congruence with traditional neuropsychological tests and usefulness in diverse cohorts remain underexplored.

METHODS AND RESULTS: A total of 406 FHS (Framingham Heart Study) and 59 BHS (Bogalusa Heart Study) participants with traditional neuropsychological tests and digital assessments using the Defense Automated Neurocognitive Assessment (DANA) smartphone protocol were included. Regression models investigated associations between DANA task digital measures and a neuropsychological global cognitive

CONCLUSIONS: Our findings demonstrate that smartphone-based cognitive assessments exhibit concurrent validity with a composite measure of traditional neuropsychological tests. This supports the potential of using smartphone-based assessments in cognitive screening across diverse populations and the scalability of digital assessments to community-dwelling individuals.