Date of Presentation
5-5-2022 12:00 AM
College
School of Osteopathic Medicine
Poster Abstract
Fibromyalgia refers to a rheumatic condition experienced as pain all over the body without a specific cause. This is considered a diagnosis of exclusion. This classification seems to suggest that any treatment options for it are purely symptomatic and are not disease targeted. Its complex diagnosis and underlying pathology contribute to the challenge of medically addressing fibromyalgia. Without a strict cause, fibromyalgia is often treated symptomatically with CBT and SNRIs. However, recent research suggests that existing therapeutic approaches are not very effective, especially when considering long term benefits for this chronic condition. This beckons for novel treatment options for these patients. Microglia have been implicated in previous studies for their role in neuropathic pain mechanisms. By considering recent advances in our knowledge of microglia, this research aims to determine the involvement of microglia in fibromyalgia pathology to hopefully identify a novel treatment target.
Keywords
Fibromyalgia, Neuralgia, Microglia, Therapeutics
Disciplines
Medicine and Health Sciences | Musculoskeletal Diseases | Nervous System Diseases | Pathological Conditions, Signs and Symptoms | Rheumatology | Therapeutics
Document Type
Poster
Included in
Musculoskeletal Diseases Commons, Nervous System Diseases Commons, Pathological Conditions, Signs and Symptoms Commons, Rheumatology Commons, Therapeutics Commons
Exploring the Viability of a Microglia Attenuating Treatment Model for Fibromyalgia Patients
Fibromyalgia refers to a rheumatic condition experienced as pain all over the body without a specific cause. This is considered a diagnosis of exclusion. This classification seems to suggest that any treatment options for it are purely symptomatic and are not disease targeted. Its complex diagnosis and underlying pathology contribute to the challenge of medically addressing fibromyalgia. Without a strict cause, fibromyalgia is often treated symptomatically with CBT and SNRIs. However, recent research suggests that existing therapeutic approaches are not very effective, especially when considering long term benefits for this chronic condition. This beckons for novel treatment options for these patients. Microglia have been implicated in previous studies for their role in neuropathic pain mechanisms. By considering recent advances in our knowledge of microglia, this research aims to determine the involvement of microglia in fibromyalgia pathology to hopefully identify a novel treatment target.