Submitting Author(s)

Rohan Yarlagadda, Rowan University

Date of Presentation

5-5-2022 12:00 AM

College

School of Osteopathic Medicine

Poster Abstract

Fibromyalgia refers to a rheumatic condition experienced as pain all over the body without a specific cause. This is considered a diagnosis of exclusion. This classification seems to suggest that any treatment options for it are purely symptomatic and are not disease targeted. Its complex diagnosis and underlying pathology contribute to the challenge of medically addressing fibromyalgia. Without a strict cause, fibromyalgia is often treated symptomatically with CBT and SNRIs. However, recent research suggests that existing therapeutic approaches are not very effective, especially when considering long term benefits for this chronic condition. This beckons for novel treatment options for these patients. Microglia have been implicated in previous studies for their role in neuropathic pain mechanisms. By considering recent advances in our knowledge of microglia, this research aims to determine the involvement of microglia in fibromyalgia pathology to hopefully identify a novel treatment target.

Keywords

Fibromyalgia, Neuralgia, Microglia, Therapeutics

Disciplines

Medicine and Health Sciences | Musculoskeletal Diseases | Nervous System Diseases | Pathological Conditions, Signs and Symptoms | Rheumatology | Therapeutics

Document Type

Poster

Share

COinS
 
May 5th, 12:00 AM

Exploring the Viability of a Microglia Attenuating Treatment Model for Fibromyalgia Patients

Fibromyalgia refers to a rheumatic condition experienced as pain all over the body without a specific cause. This is considered a diagnosis of exclusion. This classification seems to suggest that any treatment options for it are purely symptomatic and are not disease targeted. Its complex diagnosis and underlying pathology contribute to the challenge of medically addressing fibromyalgia. Without a strict cause, fibromyalgia is often treated symptomatically with CBT and SNRIs. However, recent research suggests that existing therapeutic approaches are not very effective, especially when considering long term benefits for this chronic condition. This beckons for novel treatment options for these patients. Microglia have been implicated in previous studies for their role in neuropathic pain mechanisms. By considering recent advances in our knowledge of microglia, this research aims to determine the involvement of microglia in fibromyalgia pathology to hopefully identify a novel treatment target.

 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.