Rowan University Faculty Research Day 2023
Stabilizing DNA and RNA for long-term room-temperature storage is important for many biotechnological applications including oncology pharmaceuticals and mRNA-based vaccines (e.g. Covid vaccines). This poster shows that ionic liquids can improve the thermal stability of G-quadruplex DNA and RNA structures, and motivates further studies of ionic liquid-based materials for DNA / RNA stabilization.
Vaden, Timothy, "Stabilizing G-quadruplex DNA and RNA structures with ionic liquids" (2023). Faculty Scholarship for the College of Science & Mathematics. 290.
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