Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications

Authors

Burcin Izbudak
Berivan Cecen
Ingrid Anaya
Amir K. Miri, Rowan UniversityFollow
Ayca Bal-Ozturk
Erdal Karaoz

Document Type

Article

Version Deposited

Published Version

Publication Date

9-9-2021

Publication Title

RSC Advances

DOI

10.1039/D1RA03978D

Abstract

Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, natural biodegradability in an acidic medium, and negligible toxicity. In this review, we study potential applications of LDH-based nanocomposite scaffolds for tissue engineering. We address how LDHs provide new solutions for nanostructure stability and enhance in vivo studies' success.

Comments

© 2021 The Author(s). Published by the Royal Society of Chemistry. This article is Open Access with a CC-BY-NC license.

Recommended Citation

Burcin Izbudak, Berivan Cecen, Ingrid Anaya, Amir K. Miri, Ayca Bal-Ozturk & Erdal Karaoz. Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications. RSC Adv., 2021,11, 30237-30252, DOI: https://doi.org/10.1039/D1RA03978D

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License