M.S. Pharmaceutical Sciences
Chemistry & Biochemistry
College of Science & Mathematics
Heterocyclic compounds; Drug development
Medicinal and Pharmaceutical Chemistry
Heterocyclic compounds play an important role in pharmaceutical drug development. Several natural products and biologically active compounds contain heterocyclic motifs in them. Multicomponent coupling reactions offer an excellent platform for the synthesis of diverse libraries of heterocyclic compounds. We have been working on the synthesis of novel heterocyclic small molecules utilizing reactions such as Baylis-Hillman reaction, Passerini reaction, Click reaction, reductive amination aldol condensation, etc.
In the current project, we prepared three series of heterocyclic compounds using Passerini and Baylis-Hillman reactions as key steps. Owing to the importance of heterocyclic chemistry in drug discovery and the ease of synthesis, the current work would be of interest to medicinal and natural product chemists.
Indukuri, Anupama, "Functionalized heterocyclics as potential therapeutics" (2019). Theses and Dissertations. 2727.