Document Type
Poster
Version Deposited
Published Version
Publication Date
12-15-2017
Publication Title
Molecular Biology of the Cell
Conference Name
ASCB/EMBO 2017 Annual Meeting
DOI
10.1091/mbc.E17-10-0618
Abstract
Cyclin C is a component of the mediator complex of RNA polymerase II that localizes to the nucleus under normal conditions. In response to stress, cyclin C translocates to the cytosol and mitochondria and mediates stress‐induced mitochondrial fission and apoptosis. The molecular mechanisms by which cyclin C induces mitochondrial fission are unknown. Using in vitro experimental approaches, we sought to investigate the mechanistic basis of cyclin C mediated mitochondrial fission.
Recommended Citation
Ganesan V, Cooper KF, Strich R. Mechanistic insights into the regulation of mitochondrial fission by cyclin C [Conference Abstract P3272, p. Tuesday 350-351]. Molecular Biology of the Cell. 2017 Dec 15;28(26):3727. doi: 10.1091/mbc.E17-10-0618. PMID: 29237772. PMCID: PMC5739290.
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Comments
Complete conference abstracts available as "Supplemental Material" at https://www.molbiolcell.org/doi/full/10.1091/mbc.E17-10-0618
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