Date of Presentation

5-5-2022 12:00 AM

College

School of Osteopathic Medicine

Poster Abstract

Working memory (WM) is the ability to store information for short periods of time and is used to execute tasks

WM has been understood to work via the medial prefrontal cortex (mPFC) and dorsal hippocampus (dHPC), but they do not directly project to each other

The nucleus reuniens of the thalamus (Re) is a “middle man” between the mPFC and dHPC

There are projections between the prelimbic cortex (PrL) and Re that may be used during WM

To test the connection of the PrL to Re, a delayed nonmatch to position (DNMTP) task was performed

Keywords

Midline Thalamic Nuclei, Hippocampus, Short-Term Memory, Thalamus, Animal Models, Rats

Disciplines

Investigative Techniques | Medical Cell Biology | Medical Neurobiology | Medicine and Health Sciences | Psychological Phenomena and Processes

Document Type

Poster

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May 5th, 12:00 AM

The Role of Corticothalamic Projections (Prelimbic Cortex to Nucleus Reuniens) in Working Memory

Working memory (WM) is the ability to store information for short periods of time and is used to execute tasks

WM has been understood to work via the medial prefrontal cortex (mPFC) and dorsal hippocampus (dHPC), but they do not directly project to each other

The nucleus reuniens of the thalamus (Re) is a “middle man” between the mPFC and dHPC

There are projections between the prelimbic cortex (PrL) and Re that may be used during WM

To test the connection of the PrL to Re, a delayed nonmatch to position (DNMTP) task was performed

 

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