Date of Presentation
5-5-2022 12:00 AM
College
School of Osteopathic Medicine
Poster Abstract
Working memory (WM) is the ability to store information for short periods of time and is used to execute tasks
WM has been understood to work via the medial prefrontal cortex (mPFC) and dorsal hippocampus (dHPC), but they do not directly project to each other
The nucleus reuniens of the thalamus (Re) is a “middle man” between the mPFC and dHPC
There are projections between the prelimbic cortex (PrL) and Re that may be used during WM
To test the connection of the PrL to Re, a delayed nonmatch to position (DNMTP) task was performed
Keywords
Midline Thalamic Nuclei, Hippocampus, Short-Term Memory, Thalamus, Animal Models, Rats
Disciplines
Investigative Techniques | Medical Cell Biology | Medical Neurobiology | Medicine and Health Sciences | Psychological Phenomena and Processes
Document Type
Poster
Included in
Investigative Techniques Commons, Medical Cell Biology Commons, Medical Neurobiology Commons, Psychological Phenomena and Processes Commons
The Role of Corticothalamic Projections (Prelimbic Cortex to Nucleus Reuniens) in Working Memory
Working memory (WM) is the ability to store information for short periods of time and is used to execute tasks
WM has been understood to work via the medial prefrontal cortex (mPFC) and dorsal hippocampus (dHPC), but they do not directly project to each other
The nucleus reuniens of the thalamus (Re) is a “middle man” between the mPFC and dHPC
There are projections between the prelimbic cortex (PrL) and Re that may be used during WM
To test the connection of the PrL to Re, a delayed nonmatch to position (DNMTP) task was performed