Date of Presentation

5-5-2022 12:00 AM

College

School of Osteopathic Medicine

Poster Abstract

Ashwagandha is a popular Ayurvedic herb that is derived from the extracts of the roots of Withania somnifera, an evergreen shrub endemic to India and Southeast Asia. It is generally utilized as a tonic to increase one’s energy and reduce stress levels. Often referred to as “Indian ginseng”, it provides neuroprotective and anti-inflammatory properties that address stress, pain, and fatigue. Additionally, it may assist in dealing with rashes, diabetes, and arthritis. It has also been shown to counteract the effects of aging. Though these properties have not been shown in prospective studies, it has become a popular product among western countries. Extracts of the herb are often supplied as tablets without few, if any, adverse reactions. Several case reports however have brought to light that taking ashwagandha may induce liver injury in patients taking commercial products that contain this extract.

Keywords

Ashwagandha, Complementary Therapies, Withania, Liver, Hepatotoxin, Herbal Medicine

Disciplines

Alternative and Complementary Medicine | Hepatology | Medicine and Health Sciences | Pathological Conditions, Signs and Symptoms | Plants

Document Type

Poster

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May 5th, 12:00 AM

An Herbal Liver Effect: Ashwagandha-Induced Hepatotoxicity

Ashwagandha is a popular Ayurvedic herb that is derived from the extracts of the roots of Withania somnifera, an evergreen shrub endemic to India and Southeast Asia. It is generally utilized as a tonic to increase one’s energy and reduce stress levels. Often referred to as “Indian ginseng”, it provides neuroprotective and anti-inflammatory properties that address stress, pain, and fatigue. Additionally, it may assist in dealing with rashes, diabetes, and arthritis. It has also been shown to counteract the effects of aging. Though these properties have not been shown in prospective studies, it has become a popular product among western countries. Extracts of the herb are often supplied as tablets without few, if any, adverse reactions. Several case reports however have brought to light that taking ashwagandha may induce liver injury in patients taking commercial products that contain this extract.

 

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