Date of Presentation
5-5-2022 12:00 AM
College
School of Osteopathic Medicine
Poster Abstract
Calciphylaxis is a rare vascular disorder that presents with painful skin necrosis due to calcium accumulation in skin and adipose tissue. Most commonly, cutaneous manifestations of calciphylaxis are seen on the buttocks, thighs and extremities. Very few cases have presented unconventional locations of these calcified eschars and ulcers such as the penis and scrotum. Risk factors for this disease include chronic kidney disease, hyperparathyroidism, long-term hemodialysis and diabetes. This case presents an atypical presentation of painless scrotal ulcers.
A high degree of clinical suspicion in patients with ESRD on HD and T2DM is needed to effectively reach a diagnosis of calciphylaxis. The high rate of mortality and morbidity coincide with the risk factors associated with this condition. Early recognition of calciphylaxis in a patient with no pain despite the presence of ulcerations warrants a closer look into their comorbidities to identify this disease on the differential as it is critical to start treatment early to prevent devastating outcomes.
Keywords
Calciphylaxis, Scrotum, Diabetes Complications, Diabetes Mellitus, Kidney Failure
Disciplines
Diagnosis | Endocrinology, Diabetes, and Metabolism | Medicine and Health Sciences | Nutritional and Metabolic Diseases | Pathological Conditions, Signs and Symptoms
Document Type
Poster
Included in
Diagnosis Commons, Endocrinology, Diabetes, and Metabolism Commons, Nutritional and Metabolic Diseases Commons, Pathological Conditions, Signs and Symptoms Commons
Painless Scrotal Ulcers Become Something Unexpected: A Rare Case of Scrotal Calciphylaxis
Calciphylaxis is a rare vascular disorder that presents with painful skin necrosis due to calcium accumulation in skin and adipose tissue. Most commonly, cutaneous manifestations of calciphylaxis are seen on the buttocks, thighs and extremities. Very few cases have presented unconventional locations of these calcified eschars and ulcers such as the penis and scrotum. Risk factors for this disease include chronic kidney disease, hyperparathyroidism, long-term hemodialysis and diabetes. This case presents an atypical presentation of painless scrotal ulcers.
A high degree of clinical suspicion in patients with ESRD on HD and T2DM is needed to effectively reach a diagnosis of calciphylaxis. The high rate of mortality and morbidity coincide with the risk factors associated with this condition. Early recognition of calciphylaxis in a patient with no pain despite the presence of ulcerations warrants a closer look into their comorbidities to identify this disease on the differential as it is critical to start treatment early to prevent devastating outcomes.