Date of Presentation

5-2-2024 12:00 AM

College

Rowan-Virtua School of Osteopathic Medicine

Poster Abstract

Introduction: Postoperative cognitive dysfunction (POCD) is a common problem in the elderly population after undergoing anesthesia that results in sometimes irreversible cognitive and physical impairment that can increase mortality and decrease quality of life.

Methods: To see the relationship between preoperative fitness capacity and how this relates to postoperative cognitive ability a literature review was performed. Studies that were included involved populations older than sixty years old that had undergone anesthesia. Additionally, animal studies were included to show inflammatory marker levels and how they increased in relation to physical activity.

Results: Various fitness scales were used such as the Timed up and Go test, 6 Minute Walking Distance, and more to compare how fitness related to postoperative function. Increased preoperative fitness in humans related to improved post-operative outcomes. Studies in mice showed that physical activity decreased inflammatory markers in aged mice compared to sedentary mice.

Conclusion: These data are promising for future prevention of POCD as exercise and fitness can be used as a tool to prevent postoperative decline. Future studies should aim to focus on particular exercises and how they affect postoperative outcomes.

Keywords

Postoperative delirium, Prehabilitation, Preoperative fitness, Inflammation, Cognitive dysfunction, Geriatrics, Postoperative Cognitive Complications, Postoperative Cognitive Dysfunction, Preoperative Exercise, Treatment Outcome

Disciplines

Anesthesia and Analgesia | Anesthesiology | Geriatrics | Health and Medical Administration | Medicine and Health Sciences | Neurology | Other Rehabilitation and Therapy | Pathological Conditions, Signs and Symptoms | Surgery | Surgical Procedures, Operative

Document Type

Poster

DOI

10.31986/issn.2689-0690_rdw.stratford_research_day.127_2024

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May 2nd, 12:00 AM

Preventing Postoperative Cognitive Dysfunction Through Preoperative Exercise

Introduction: Postoperative cognitive dysfunction (POCD) is a common problem in the elderly population after undergoing anesthesia that results in sometimes irreversible cognitive and physical impairment that can increase mortality and decrease quality of life.

Methods: To see the relationship between preoperative fitness capacity and how this relates to postoperative cognitive ability a literature review was performed. Studies that were included involved populations older than sixty years old that had undergone anesthesia. Additionally, animal studies were included to show inflammatory marker levels and how they increased in relation to physical activity.

Results: Various fitness scales were used such as the Timed up and Go test, 6 Minute Walking Distance, and more to compare how fitness related to postoperative function. Increased preoperative fitness in humans related to improved post-operative outcomes. Studies in mice showed that physical activity decreased inflammatory markers in aged mice compared to sedentary mice.

Conclusion: These data are promising for future prevention of POCD as exercise and fitness can be used as a tool to prevent postoperative decline. Future studies should aim to focus on particular exercises and how they affect postoperative outcomes.

 

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