Date of Presentation
5-2-2024 12:00 AM
College
Rowan-Virtua School of Osteopathic Medicine
Poster Abstract
Introduction: Postoperative cognitive dysfunction (POCD) is a common problem in the elderly population after undergoing anesthesia that results in sometimes irreversible cognitive and physical impairment that can increase mortality and decrease quality of life.
Methods: To see the relationship between preoperative fitness capacity and how this relates to postoperative cognitive ability a literature review was performed. Studies that were included involved populations older than sixty years old that had undergone anesthesia. Additionally, animal studies were included to show inflammatory marker levels and how they increased in relation to physical activity.
Results: Various fitness scales were used such as the Timed up and Go test, 6 Minute Walking Distance, and more to compare how fitness related to postoperative function. Increased preoperative fitness in humans related to improved post-operative outcomes. Studies in mice showed that physical activity decreased inflammatory markers in aged mice compared to sedentary mice.
Conclusion: These data are promising for future prevention of POCD as exercise and fitness can be used as a tool to prevent postoperative decline. Future studies should aim to focus on particular exercises and how they affect postoperative outcomes.
Keywords
Postoperative delirium, Prehabilitation, Preoperative fitness, Inflammation, Cognitive dysfunction, Geriatrics, Postoperative Cognitive Complications, Postoperative Cognitive Dysfunction, Preoperative Exercise, Treatment Outcome
Disciplines
Anesthesia and Analgesia | Anesthesiology | Geriatrics | Health and Medical Administration | Medicine and Health Sciences | Neurology | Other Rehabilitation and Therapy | Pathological Conditions, Signs and Symptoms | Surgery | Surgical Procedures, Operative
Document Type
Poster
DOI
10.31986/issn.2689-0690_rdw.stratford_research_day.127_2024
Included in
Anesthesia and Analgesia Commons, Anesthesiology Commons, Geriatrics Commons, Health and Medical Administration Commons, Neurology Commons, Other Rehabilitation and Therapy Commons, Pathological Conditions, Signs and Symptoms Commons, Surgery Commons, Surgical Procedures, Operative Commons
Preventing Postoperative Cognitive Dysfunction Through Preoperative Exercise
Introduction: Postoperative cognitive dysfunction (POCD) is a common problem in the elderly population after undergoing anesthesia that results in sometimes irreversible cognitive and physical impairment that can increase mortality and decrease quality of life.
Methods: To see the relationship between preoperative fitness capacity and how this relates to postoperative cognitive ability a literature review was performed. Studies that were included involved populations older than sixty years old that had undergone anesthesia. Additionally, animal studies were included to show inflammatory marker levels and how they increased in relation to physical activity.
Results: Various fitness scales were used such as the Timed up and Go test, 6 Minute Walking Distance, and more to compare how fitness related to postoperative function. Increased preoperative fitness in humans related to improved post-operative outcomes. Studies in mice showed that physical activity decreased inflammatory markers in aged mice compared to sedentary mice.
Conclusion: These data are promising for future prevention of POCD as exercise and fitness can be used as a tool to prevent postoperative decline. Future studies should aim to focus on particular exercises and how they affect postoperative outcomes.