Date of Presentation

5-2-2024 12:00 AM

College

Rowan-Virtua School of Osteopathic Medicine

Poster Abstract

Background: One in 36 children in the United States are diagnosed with Autism Spectrum Disorder (ASD). Although heritability of the condition ranges from 40 to 80%, other factors such as vitamin levels, may have a significant impact on the risk of development. These vitamins include D, B12, and B9.

Purpose: To assess the impact vitamin supplementation has on behaviors associated with ASD, and to determine which specific aspects of ASD may be improved with vitamin supplementation.

Methods: A literature review was performed. The search was utilized PubMed, JSTOR and Web of Science. Keyword strings included: “Vitamin D B12 B9 folate cobalamin supplementation brain autism spectrum disorder neurological development”, “Vitamin D B12 B9 folate cobalamin supplementation brain autism spectrum disorder neurological development”, and “Vitamin D B12 B9 folate cobalamin supplementation brain autism spectrum disorder neurological development”

Results: Supplementation with Vitamin D was associated with decreases in both irritability and hyperactivity. Vitamin B12 Supplementation showed improvements in several behaviors including hyperactivity, tantrumming and receptive language. Vitamin B9 Supplementation was associated with an improvement in verbal communication and may be indicated as an effective adjunct therapy to structured teaching programs.

Conclusions: Although each form of supplementation was associated with positive behavior changes, the research included contradicting outcomes and further research is warranted to strengthen existing conclusions.

Keywords

Autism Spectrum Disorder, ASD, Vitamin D, Vitamin B12, Vitamin B9, Folate, Vitamin Supplementation, Dietary Supplements, Vitamins

Disciplines

Alternative and Complementary Medicine | Behavioral Medicine | Behavior and Behavior Mechanisms | Chemical Actions and Uses | Congenital, Hereditary, and Neonatal Diseases and Abnormalities | Health and Medical Administration | Integrative Medicine | Investigative Techniques | Medicine and Health Sciences | Nervous System Diseases | Neurology | Therapeutics

Document Type

Poster

DOI

10.31986/issn.2689-0690_rdw.stratford_research_day.187_2024

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May 2nd, 12:00 AM

The Impact of Vitamin Supplementation (D, B12, B9) on Behaviors Associated with Autism Spectrum Disorder

Background: One in 36 children in the United States are diagnosed with Autism Spectrum Disorder (ASD). Although heritability of the condition ranges from 40 to 80%, other factors such as vitamin levels, may have a significant impact on the risk of development. These vitamins include D, B12, and B9.

Purpose: To assess the impact vitamin supplementation has on behaviors associated with ASD, and to determine which specific aspects of ASD may be improved with vitamin supplementation.

Methods: A literature review was performed. The search was utilized PubMed, JSTOR and Web of Science. Keyword strings included: “Vitamin D B12 B9 folate cobalamin supplementation brain autism spectrum disorder neurological development”, “Vitamin D B12 B9 folate cobalamin supplementation brain autism spectrum disorder neurological development”, and “Vitamin D B12 B9 folate cobalamin supplementation brain autism spectrum disorder neurological development”

Results: Supplementation with Vitamin D was associated with decreases in both irritability and hyperactivity. Vitamin B12 Supplementation showed improvements in several behaviors including hyperactivity, tantrumming and receptive language. Vitamin B9 Supplementation was associated with an improvement in verbal communication and may be indicated as an effective adjunct therapy to structured teaching programs.

Conclusions: Although each form of supplementation was associated with positive behavior changes, the research included contradicting outcomes and further research is warranted to strengthen existing conclusions.

 

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