Date of Presentation

5-2-2024 12:00 AM

College

Rowan-Virtua School of Osteopathic Medicine

Poster Abstract

Polycystic ovary syndrome (PCOS) affects approximately 6 to 13% of adolescent girls in the United States.6 PCOS poses difficulty with diagnosing and treatment with adolescents as its symptoms are heterogenous and are often rationalized with other diagnoses. Key diagnostic features of PCOS include irregular menstruation, infertility, obesity, hirsutism, increased risk of diabetes mellitus, hypertension, lipid abnormalities and metabolic syndrome.12 Currently, there are no pharmacological therapies approved by the FDA to treat PCOS.5 Alternatives include pharmacological management of symptoms with medications like combined oral contraceptive pills, metformin and anti-obesity agents.6 Recently, more discussion about the lack of PCOS treatment has been circulating social media sites like TikTok and Youtube, platforms that have large adolescent audiences. With this discussion, there has been a large focus on using myo-inositol (MI), a supplement that is available over the counter, to treat PCOS. MI is a manufactured derivative of the body’s inositol that is used to reduce insulin resistance, improve ovarian function and lower androgen levels in females with PCOS.4 Understanding the efficacy of MI is vital across all medical specialties, as its mechanism affects the entire body and overall health.

Keywords

PCOS, Polycystic Ovary Syndrome, Adolescent, Female, teenager, myo-inositol, endocrine, treatment outcome, efficacy, scoping review

Disciplines

Alternative and Complementary Medicine | Female Urogenital Diseases and Pregnancy Complications | Hormones, Hormone Substitutes, and Hormone Antagonists | Medicine and Health Sciences | Obstetrics and Gynecology | Pathological Conditions, Signs and Symptoms | Therapeutics

Document Type

Poster

DOI

10.31986/issn.2689-0690_rdw.stratford_research_day.196_2024

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May 2nd, 12:00 AM

Investigating the Efficacy of Myo-Inositol in Adolescents with Polycystic Ovary Syndrome: A Scoping Review

Polycystic ovary syndrome (PCOS) affects approximately 6 to 13% of adolescent girls in the United States.6 PCOS poses difficulty with diagnosing and treatment with adolescents as its symptoms are heterogenous and are often rationalized with other diagnoses. Key diagnostic features of PCOS include irregular menstruation, infertility, obesity, hirsutism, increased risk of diabetes mellitus, hypertension, lipid abnormalities and metabolic syndrome.12 Currently, there are no pharmacological therapies approved by the FDA to treat PCOS.5 Alternatives include pharmacological management of symptoms with medications like combined oral contraceptive pills, metformin and anti-obesity agents.6 Recently, more discussion about the lack of PCOS treatment has been circulating social media sites like TikTok and Youtube, platforms that have large adolescent audiences. With this discussion, there has been a large focus on using myo-inositol (MI), a supplement that is available over the counter, to treat PCOS. MI is a manufactured derivative of the body’s inositol that is used to reduce insulin resistance, improve ovarian function and lower androgen levels in females with PCOS.4 Understanding the efficacy of MI is vital across all medical specialties, as its mechanism affects the entire body and overall health.

 

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