College
Rowan-Virtua School of Osteopathic Medicine
Keywords
serotonin syndrome, tricyclic antidepressant
IRB or IACUC Protocol Number
G24082
Date of Presentation
5-1-2025 12:00 AM
Poster Abstract
Serotonin syndrome, a potentially life-threatening condition, can be challenging to diagnose due to its diverse etiology and varied symptomatology. Despite its severity, serotonin syndrome may present from mild to fatal, with symptoms such as autonomic instability, altered mental status, and neuromuscular excitation (e.g. muscle rigidity, hyperreflexia). Here, we present a 20-year-old male with an extensive psychiatric history who was prescribed clomipramine and developed serotonin syndrome. Few cases of serotonin syndrome have been reported to date, exacerbating the difficulty in recognizing and quickly treating such cases. Cases of serotonin syndrome should continue to be reported, in order to familiarize clinicians with varied presentations of this toxicity.
Disciplines
Emergency Medicine | Heterocyclic Compounds | Medicine and Health Sciences | Pathological Conditions, Signs and Symptoms | Psychiatry | Therapeutics
Included in
Emergency Medicine Commons, Heterocyclic Compounds Commons, Pathological Conditions, Signs and Symptoms Commons, Psychiatry Commons, Therapeutics Commons
Identifying Early Presentation of Serotonin Syndrome in a 20-year-old Male Prescribed Clomipramine and Quetiapine: A Case Report
Serotonin syndrome, a potentially life-threatening condition, can be challenging to diagnose due to its diverse etiology and varied symptomatology. Despite its severity, serotonin syndrome may present from mild to fatal, with symptoms such as autonomic instability, altered mental status, and neuromuscular excitation (e.g. muscle rigidity, hyperreflexia). Here, we present a 20-year-old male with an extensive psychiatric history who was prescribed clomipramine and developed serotonin syndrome. Few cases of serotonin syndrome have been reported to date, exacerbating the difficulty in recognizing and quickly treating such cases. Cases of serotonin syndrome should continue to be reported, in order to familiarize clinicians with varied presentations of this toxicity.
