Faculty mentor/PI email address
scheinth@rowan.edu
Is your research Teaching and Learning based?
1
Keywords
Obsessive compulsive disorder, OCD, dementia
Date of Presentation
5-6-2026 12:00 AM
Poster Abstract
Obsessive-compulsive disorder (OCD) is a chronic psychiatric condition typically characterized by intrusive thoughts and repetitive behaviors with preserved insight. Dementia, a progressive neurocognitive disorder, is frequently associated with behavioral and psychiatric symptoms; however, its impact on pre-existing OCD is less well understood.
Subject of study includes evaluation of neurodegenerative processes to exacerbate pre-existing OCD symptoms. Evidence suggests that dysfunction in shared fronto-striatal circuits—particularly involving the orbitofrontal cortex and basal ganglia—may underlie this relationship. Additionally, cognitive impairment may reduce the ability to inhibit intrusive thoughts, further reinforcing compulsive behaviors. Emerging research also indicates a bidirectional association, with OCD linked to an increased risk of subsequent dementia.
Importantly, OCD in older adults may be misdiagnosed as a psychotic disorder, particularly when insight diminishes and obsessive thoughts appear delusional. Distinguishing between these conditions is critical, as management strategies differ significantly.
This review underscores the importance of comprehensive neuropsychiatric evaluation in elderly patients with worsening OCD symptoms. Early recognition of the interaction between OCD and dementia can improve diagnostic accuracy and guide appropriate treatment, ultimately enhancing patient outcomes and reducing caregiver burden.
Disciplines
Medicine and Health Sciences | Mental Disorders | Psychological Phenomena and Processes
Worsening Obsessive Compulsive Disorder (OCD) with new onset Dementia
Obsessive-compulsive disorder (OCD) is a chronic psychiatric condition typically characterized by intrusive thoughts and repetitive behaviors with preserved insight. Dementia, a progressive neurocognitive disorder, is frequently associated with behavioral and psychiatric symptoms; however, its impact on pre-existing OCD is less well understood.
Subject of study includes evaluation of neurodegenerative processes to exacerbate pre-existing OCD symptoms. Evidence suggests that dysfunction in shared fronto-striatal circuits—particularly involving the orbitofrontal cortex and basal ganglia—may underlie this relationship. Additionally, cognitive impairment may reduce the ability to inhibit intrusive thoughts, further reinforcing compulsive behaviors. Emerging research also indicates a bidirectional association, with OCD linked to an increased risk of subsequent dementia.
Importantly, OCD in older adults may be misdiagnosed as a psychotic disorder, particularly when insight diminishes and obsessive thoughts appear delusional. Distinguishing between these conditions is critical, as management strategies differ significantly.
This review underscores the importance of comprehensive neuropsychiatric evaluation in elderly patients with worsening OCD symptoms. Early recognition of the interaction between OCD and dementia can improve diagnostic accuracy and guide appropriate treatment, ultimately enhancing patient outcomes and reducing caregiver burden.