Faculty mentor/PI email address
hurst@rowan.edu
Keywords
ethics; informed consent; islets; type 1 diabetes; xenotransplantation
Date of Presentation
5-6-2026 12:00 AM
Poster Abstract
Purpose: The objective of this review is to systematically map and synthesize the existing literature regarding informed consent for porcine islet xenotransplantation for the treatment of Type 1 Diabetes.
Methods: The search was conducted in May 2025 through the following databases: PubMed, SCOPUS, EMBASE, and CINAHL. Broad search strings were used to combine the text words “islet” AND “xenotransplantation” AND “consent” or similar permutations and combinations. Peer-reviewed articles were included if they were published between January 1990 and May 2025 and written in English. The final search results were manually exported to a reference manager system (Zotero), and the PRISMA-ScR flow diagram was created to depict the data extraction process.
Results: From 134 sources, 7 articles met eligibility for this scoping review. Although clinical studies have been sporadically conducted, there is a lack of literature describing informed consent for islet xenotransplantation.
Conclusion: This review has highlighted a scarcity of scholarly discourse and published guidance on informed consent specifically in the context of islet xenotransplantation.
Disciplines
Bioethics and Medical Ethics | Medicine and Health Sciences | Nutritional and Metabolic Diseases
Informed Consent for Porcine Islet Xenotransplantation to Treat Type 1 Diabetes: A Scoping Review
Purpose: The objective of this review is to systematically map and synthesize the existing literature regarding informed consent for porcine islet xenotransplantation for the treatment of Type 1 Diabetes.
Methods: The search was conducted in May 2025 through the following databases: PubMed, SCOPUS, EMBASE, and CINAHL. Broad search strings were used to combine the text words “islet” AND “xenotransplantation” AND “consent” or similar permutations and combinations. Peer-reviewed articles were included if they were published between January 1990 and May 2025 and written in English. The final search results were manually exported to a reference manager system (Zotero), and the PRISMA-ScR flow diagram was created to depict the data extraction process.
Results: From 134 sources, 7 articles met eligibility for this scoping review. Although clinical studies have been sporadically conducted, there is a lack of literature describing informed consent for islet xenotransplantation.
Conclusion: This review has highlighted a scarcity of scholarly discourse and published guidance on informed consent specifically in the context of islet xenotransplantation.