Faculty mentor/PI email address
jim010@aol.com
Is your research Teaching and Learning based?
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Keywords
Infective endocarditis; Escherichia coli; pulmonic valve endocarditis; spinal epidural abscess; ascending cholangitis; gram-negative bacteremia; intravenous drug use; emergency medicine.
Date of Presentation
5-6-2026 12:00 AM
Poster Abstract
Infective endocarditis (IE) is most commonly caused by gram-positive organisms, while Escherichia coli accounts for less than 1% of reported cases. Pulmonic valve involvement is particularly rare, representing fewer than 2% of IE cases. We report a case of E. coli infective endocarditis involving the pulmonic valve complicated by spinal epidural abscess and ascending cholangitis in a patient with intravenous drug use. Blood cultures demonstrated persistent E. coli bacteremia, and further evaluation with echocardiography and MRI revealed pulmonic valve vegetations and epidural abscess. This case highlights the importance of evaluating persistent gram-negative bacteremia for infective endocarditis and metastatic infection.
Disciplines
Bacterial Infections and Mycoses | Cardiovascular Diseases | Medicine and Health Sciences
Gram-Negative Infective Endocarditis : A Rare Case of Escherichia coli Pulmonic Valve Endocarditis
Infective endocarditis (IE) is most commonly caused by gram-positive organisms, while Escherichia coli accounts for less than 1% of reported cases. Pulmonic valve involvement is particularly rare, representing fewer than 2% of IE cases. We report a case of E. coli infective endocarditis involving the pulmonic valve complicated by spinal epidural abscess and ascending cholangitis in a patient with intravenous drug use. Blood cultures demonstrated persistent E. coli bacteremia, and further evaluation with echocardiography and MRI revealed pulmonic valve vegetations and epidural abscess. This case highlights the importance of evaluating persistent gram-negative bacteremia for infective endocarditis and metastatic infection.