Publication Date
October 2020
DOI
10.31986/issn.2578-3343_vol1iss2.2
First Page
20
Last Page
36
Abstract
The purpose of this review is to summarize the recent literature focusing on intravenous (IV) administration of commonly used anesthetics, including midazolam, pentobarbital/ thiopental, propofol, and ketamine in the treatment of status epilepticus (SE). Anesthetics should be reserved as third-line therapy for the treatment of SE when benzodiazepines and other second-line agents fail to terminate the seizure. We have reviewed the literature related to the treatment of status epilepticus, refractory status epilepticus, super-refractory status epilepticus, anesthetics, midazolam, pentobarbital/thiopental, propofol, and ketamine. This paper focuses on the pharmacology, dosages, major side effects, and clinical use of IV anesthetics in the treatment of SE with an emphasis on the developing literature supporting the use of ketamine for this indication. Based on the available literature, we propose recommendations for third-line agent selection in the management of SE.
Recommended Citation
Yilmaz, Furkan M. MD.; Igneri, Lauren A. PharmD; Yilmaz, Yasir A. MD.; and Burakgazi-Dalkilic, Evren MD.
(2020)
"Anesthetic Use In Status Epilepticus: A Concise Review,"
Cooper Rowan Medical Journal: Vol. 2:
Iss.
1, Article 2.
DOI: 10.31986/issn.2578-3343_vol1iss2.2
Available at:
https://rdw.rowan.edu/crjcsm/vol2/iss1/2
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Included in
Anesthesia and Analgesia Commons, Critical Care Commons, Nervous System Diseases Commons, Neurology Commons, Therapeutics Commons
