Advances in ultra-high-pressure and multi-dimensional liquid chromatography instrumentation and workflows
The present contribution discusses recent advances in ultra-high-pressure liquid chromatography (UHPLC) and multi-dimensional liquid chromatography (MDLC) technology. First, new developments in UHPLC column technology and system design are highlighted. The latter includes a description of a novel injector concept enabling method speed-up, emerging detectors, and instrument diagnostics approaches. Next, online MDLC workflows are reviewed and advances in modulation technology are highlighted. Finally, key applications published in 2020 are reviewed.
Jelle De Vos, Dwight Stoll, Stephan Buckenmaier, Sebastiaan Eeltink, & James P. Grinias. (2021) Advances in ultra-high-pressure and multi-dimensional liquid chromatography instrumentation and workflows. Chemistry Europe, Vol. 2, Iss. 3-4, April 2021, pp. 171-192.
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© 2021 The Authors. Analytical Science Advances published by Wiley-VCH GmbH This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.