Document Type

Article

Version Deposited

Published Version

Open Access Funding Source

Open Access Publishing Fund

Publication Date

11-17-2022

Publication Title

Frontiers in Bioengineering and Biotechnology

DOI

10.3389/fbioe.2022.1047851

Abstract

Electroporation-based technologies using microsecond pulsed electric field (µsPEF) exposures are established as laboratory and clinical tools that permeabilize cell membranes. We demonstrate a µsPEF bioeffect on nucleocytoplasmic import and export of enzymes that regulate genetic expression, histone deacetylases (HDAC) -4 and -5. Their μsPEF-induced nucleocytoplasmic transport depends on presence and absence of extracellular calcium ions (Ca

Comments

Copyright © 2022 Safaei and Thompson. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).

Publication of this article was supported by the 2022-23 Rowan University Libraries Open Access Publishing Fund.

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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