Date Approved
8-25-2025
Embargo Period
8-25-2025
Document Type
Dissertation
Degree Name
Ph.D. Biochemistry
Department
Chemistry and Biochemistry
College
College of Science & Mathematics
Advisor
Subash Jonnalagadda, Ph.D.
Committee Member 1
Manoj Pandey, Ph.D.
Committee Member 2
Lark Perez, Ph.D.
Committee Member 3
Darren Boehning, Ph.D.
Committee Member 4
Kandalam Ramanujachary, Ph.D.
Abstract
This doctoral thesis explores the discovery and characterization of two novel small molecules, designated as KS100 and (R,S’)-MNF, with potential anti-cancer properties. The study encompasses a comprehensive investigation into the molecular mechanisms underlying the anti-cancer effects of these compounds, as well as their therapeutic potential in preclinical models. These findings highlight the potential of KS100 and (R,S’)-MNF as lead candidates for cancer therapy, paving the way for further preclinical development and clinical translation.
Recommended Citation
Chitren, Robert John, "DEVELOPMENT OF NOVEL SMALL MOLECULES AS POTENTIAL ANTI CANCER AGENTS" (2025). Theses and Dissertations. 3441.
https://rdw.rowan.edu/etd/3441
