Date of Presentation
4-23-2024 11:00 AM
College
College of Science & Mathematics
Faculty Sponsor(s)
Dr. Lark Perez
Poster Abstract
Antibiotic Resistance is one of the most urgent global threat to humankind. Most antibiotics are hydrophilic in nature while proteins and peptides are lipophilic. Enhancing lipophilicity of the antibiotic by HIP can increase solubility of the drugs in human and improve antibacterial effect as well. We hypothesized that formation of a hydrophobic drug complex would change the physical properties of the antibiotic and enhance its antimicrobial activity.
Student Keywords
Antibiotic Properties, Meropenem, Hydrophobic Ion-Pairing
Disciplines
Chemistry
Document Type
Poster
Included in
Enhancing the Antibiotic Properties of Meropenem with Hydrophobic Ion-Pairing
Antibiotic Resistance is one of the most urgent global threat to humankind. Most antibiotics are hydrophilic in nature while proteins and peptides are lipophilic. Enhancing lipophilicity of the antibiotic by HIP can increase solubility of the drugs in human and improve antibacterial effect as well. We hypothesized that formation of a hydrophobic drug complex would change the physical properties of the antibiotic and enhance its antimicrobial activity.