Graduate School of Biomedical Sciences Theses and Dissertations | Rowan-Virtua School of Translational Biomedical Engineering & Sciences | Rowan University
 

This contains digital theses and dissertations written by students in degree programs in the Rowan-Virtua Graduate School of Biomedical Sciences (GSBS), formerly known as Rowan GSBS. In 2023, this school was dissolved and its programs integrated into the Rowan-Virtua School of Translational Biomedical Engineering & Sciences.

If you are the author of a thesis or dissertation produced before September 2023 and do not want your document to be publicly available in Rowan Digital Works, you must complete and submit this form to request its removal from the repository.

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Theses/Dissertations from 2023

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Modeling the Tripartite Role of Cyclin C in Cellular Stress Response Coordination, Steven J. Doyle

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Med13 Degradation Defines a New Receptor-Mediated Autophagy Pathway Activated by Nutrient Deprivation, Sara E. Hanley

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Immunomodulatory Effects of Resolvin D2 in a Model of Infection, Prem Yugandhar Kadiyam Sundarasivarao

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Role of Chronic Stress-Induced Neuroinflammation in Rodent Locus Coeruleus Physiology and Anxiety-Like Behaviors, Arthur Anthony Alfonso Reyes

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The Effects of Specialized Pro-Resolving Mediator Lipoxin A4 on Pseudomonas aeruginosa Biofilms and Interactions with Monocytes, Julianne M. Thornton

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Investigating the Antibacterial and Immunomodulatory Properties of Lactobacillus acidophilus Postbiotics, Rachael M. Wilson

Theses/Dissertations from 2022

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Investigating the Role of The Basolateral Amygdala Plays in the Incubation of Cue-Induced Cocaine Seeking Behavior, Claire Marie Corbett

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DPC29 Promotes Mitochondrial Translation Post-Initation in Saccharomyces cerevisiae, Kyle Andrew Hubble

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Dual Mechanisms Implemented by LIN-28 for Positive Regulation OF HBL-1 Are Necessary for Proper Development of Distinct Tissues in Caenorhabditis elegans, Madeleine Minutillo

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The Effects Of Stress On The Mammalian Nucleolus And Ribosome Synthesis, Russell T. Sapio

Theses/Dissertations from 2021

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Long-Term Impacts of Acute Stressor Exposure on Locus Coeruleus Function and Anxiety-Like Behavior in Rats, Olga Borodovitsyna

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Investigations in the Cellular and Molecular Biology of Human Airway Mucociliary Tissue, Vincent Manna

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Differentiating the Mechanistic Role and Chemotherapeutic Potential of SRC and Podoplanin in Oncogenic Transformation, Edward P. Retzbach

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Contact Normalization and the Role of Maackia amurensis Seed Lectin as a Novel Chemotherapeutic and Antiviral Agent, Stephanie A. Sheehan

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Cyclin C Determines Cell Fate in Response to Oxidative Stress and Proteasome Inhibition, David C. Stieg

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Effects of Trans-Acting Factors on the Translational Machinery in Yeast, Brandon M. Trainor

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A High-Throughput Approach to Characterizing ARV1 on the Regulation of Lipid Homeostasis Uncovers a Novel Interaction with Epidermal Growth Factor Receptor, Nicholas Anthony Wachowski

Theses/Dissertations from 2020

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Elucidation of the Mechanisms By Which Anesthetics Induce Blood-Brain Barrier Breakdown and Delirium in the Elderly, George A. Godsey II

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Effect of S100B Deletion on Membrane Properties and Localization of NCALD and HPCA, Natasha Hesketh

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The Autoimmune System: The Effect of Physiological Stressors on Autoantibody Glycosylation and Fidelity of Autoantibody Profiles, Rahil Kheirkhah

Theses/Dissertations from 2019

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A Dedicated Chaperone Mediates the Safe Transfer of Mitoribosomal Proteins to Their Site of Assembly, Gabrielle Ashley Hillman

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A High Throughput Assay for the Detection of Stimulator of Interferon Genes (STING) Agonists, Michael J. Ingling

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Characterization of Human dUTPase, Shawna Marie Rotoli

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Natural Autoantibodies: Origin, Function and Utility for Diagnosis of Disease, Abhirup Sarkar

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The Effect of Intracellular Zinc Levels in Escherichia coli on Metallo-β-Lactamase Activity, Jill Thompson

Theses/Dissertations from 2018

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Inhibition of Ribosome Biogenesis Through Genetic and Chemical Approaches, Leonid Anikin

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Insight into Translational Activation in Yeast Mitochondria, Julia Lynn Jones

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Loss of mARV1 Promotes CHOP Signaling in Mouse Liver, Shad Anthony Mitchell

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The Role of Developmental Timing Regulators in Progenitor Proliferation and Cell Fate Specification During Mammalian Neurogenesis, Jennifer S. Romer-Seibert

Theses/Dissertations from 2017

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Characterization of E-Cadherin Regulation in Response to ZEB1 Inhibition in Endometrial Cancer Cell Lines, Chidozie Paul Chukwu

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A Lipid Binding Structure and Functional Analysis of Human ARV1, Jessie Lee Cunningham

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Development of Cellular Assays to Monitor Enzymatic and Biological Activity of CD73: A Key Modulator of Anti-Tumor Immune Response, Alexandra Fanuka

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The Role of the Expansion Segment 7 of 25S rRNA During Oxidative Stress in Saccharomyces cerevisiae, Ethan Gardner

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Mapping the Interaction Between LRRC59 and CIP2A Oncoprotein, Tamika C. Reed

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Characterization of MALT1 Inhibitors and Their Effect on Leukemic Cell Growth Properties, Christina Snyder

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Molecular Mechanisms of DNA Replication Initiation in HPVs with Genetic Variations Leading to Cellular Carcinogenesis, Gulden Yilmaz

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Brain Energy Homeostasis and the Regulation of N-acetyl-aspartate Metabolism in Development and Disease, Samantha Zaroff

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Chaperoning EF Hands that Shape Calcium Response: NCALD, HPCA and S100B, Jingyi Zhang

Theses/Dissertations from 2016

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Replication-Transciption Switch in Human Mitochondria, Karen Agaronyan

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Hexokinase II Localization is Independent of AMPK Activation in HeLa Cells, Alyssa Brown

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Utility and Origin of Blood-Based Autoantibodies for Early Detection and Diagnosis of Neurodegenerative Diseases, Cassandra DeMarshall

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Neurocalcin ẟ Response to Calcium: Which EF Hand Matters the Most?, Trokon Fiawoo

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Blood-Tissue Barriers and Autoantibodies in Neurodegenerative Disease Pathogenesis: An Approach to Diagnostics and Disease Mechanism, Eric Luria Goldwaser

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Functional Analysis of Rpl22: Coordinating Differentiation Signals and Developmental Gene Translation to Promote Cell Fate Decisions, Stephen Kim

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Characterization of Bacterial Pathogens Involved in Aerobic Vaginitis: Prevalence, Strain Characterization and Sequelae, Leslie A. Lafferty

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Punctuated Evolution Within a Eurythermic Genus (Mesenchytraeus) of Segmented Worms: Genetic Modification of the Glacier Ice Worm F1F0 ATP Synthase, Shirley A. Lang

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Assembly and Structure of Human Mitochondrial Transcription Initiation Complex, Yaroslav Morozov

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The Role of E. coli Transcript-Cleavage Factors GRE in Transcriptional Regulation Under Hyperosmotic Stress, Kseniya Obraztsova

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The Genetic Hierarchy of the Heterochronic Pathway in C. elegans, Jennifer Tsialikas

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Understanding the Differences Between Neuronal Calcium Sensor Proteins: A Comparison of Neurocalcin Delta and Hippocalcin, Jeffrey M. Viviano

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The Role of Neurovascular Compromise, Autoimmune Antibodies and Neuronal Calcium Sensor Proteins During the Onset and Progression of Alzheimer's Disease - Linking the Retina with the Brain, Hao Wu

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MicroRNA-Target Interactions in Embryonic Stem Cells, Shuang Wu

Theses/Dissertations from 2015

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Age-Dependent Breakdown of the Blood Brain Barrier and Associated Changes in S100B KO Mice, Eric V. Brown

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Structural and Functional Interactions Between Bro1 Domain of Human ALIX Protein And Nucleocapsid Packaging RNA Complex from HIV, Scott Gross

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The Development of a Platform for Expression and Purification of the Mammalian Transmembrane Transporter ABCA4, Amaryllis Ortiz

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Conformational Dynamics of DnaA Protein of Bacillus anthracis in the Initiation of DNA Replication: A Fluorescence Resonance Energy Transfer Study, Meera J. Patel

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Hippocalcin Response to Calcium: Do Conserved Tryptophans – W30 or W103 – Matter?, Sunkesula K. Sagar

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Genome Engineering to Create Dominant Alleles in Caenorhabditis elegans Using CRISPR-CAS9 Technology, Abrar Sulaimani

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Evolution of Sperm Activation in Nematodes, Qing Wei

Theses/Dissertations from 2014

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Structural and Functional Analysis of hARV1 Lipid Binding, Jamie Francisco

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The Development of a Comprehensive Antifungal Susceptibility Testing Assay for Vulvovaginal Candidiasis Therapy, David Hardaker

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Novel Biomarkers Can Be Used as Targets to Combat Cancer, Harini Krishnan

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Meiotic Checkpoint Activation Promotes Anaphase Promoting Complex/Cyclosome Substrate Specificity and UME6/SIN3/RPD3-Independent Reduction in EMG Expression, Rebecca Lewandowski

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Analysis of the Regulation and Function of CIP2A to Identify Candidate Biomarkers for Prostate Cancer, Diana Savoly

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Regulation of Strand-Specific Processing in Human Pre-mIR-371 and Its Mouse Homologs, Jianting Shi

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Molecular Pap Biomarkers for Cervical Cancer Risk Assessment in ThinPrep® Clinical Specimens, Jennifer Taylor

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The Role of Mammalian Cyclin C in Stress Response and Thyroid Disease Progression, Kun Wang

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Quality Control and Stress Response in Mammalian Ribosome Biogenesis, Minshi Wang

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The Effects of Lipoxin A4 (LXA4) on Neutrophil Biology in Sepsis, Benedict Wu

Theses/Dissertations from 2013

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Diabetes Mellitus and Hypercholesterolemia are Risk Factors for Alzheimer’s Disease and Appear to Affect the Integrity of the Blood Brain Barrier, Jacqueline Dash

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Med13p Prevents Stress-Independent Mitochondrial Hyperfragmentation and Aberrant Apoptosis Activation in Saccharomyces cerevisiae by Controlling Cyclin C Nuclear Localization, Svetlana Khakhina

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Bacterial Transcription Factors GreA, GreB and DksA: Characterization of Their Interaction with RNA Polymerase and Molecular Mechanism of Action, Andrey Parshin

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Generation and Characterization of Peptide Fusion Proteins, Brianna L. Probasco

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Modulation of Bax/Bak Dependent Apoptosis by Sirtuin 3 and Mitochondrial Permeability Transition by Sirtuin 4, Manish Verma